Immunoglobulin Fab Fragments

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

Also Known As:

Fab Immunoglobulin Fragments; Immunoglobulin Fab Fragment; Immunoglobulins, Fab; Fab Fragment Immunoglobulins; Fab Fragment, Immunoglobulin; Fab Fragments, Immunoglobulin; Fragment Immunoglobulins, Fab; Fragment, Fab; Immunoglobulin Fragments, Fab; Fab Fragment; Fab Fragments; Ig Fab Fragments; Immunoglobulins, Fab Fragment

Pharmalogical Action Categories:

Immunologic Factors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Immunoglobulin Fragments: 976
        Immunoglobulin Fab Fragments: 769
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Immunoglobulin Fragments: 976
        Immunoglobulin Fab Fragments: 769
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Immunoglobulin Fragments: 976
        Immunoglobulin Fab Fragments: 769
- Peptides: 82426
  - Peptide Fragments: 373
    - Immunoglobulin Fragments: 976
      - Immunoglobulin Fab Fragments: 769

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